The 2-Minute Rule for EAM-2201
The 2-Minute Rule for EAM-2201
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This article won't comprise any scientific tests with residing human individuals or animals carried out by any from the authors. The Assessment of harmful substances including the metabolites with the cadaver was permitted by judicial authorities and supported by Formal documentation.
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Twelve metabolites of a synthetic cannabinoid, EAM-2201, were being tentatively determined in human hepatocytes in vitro, and in human liver and urine specimens in vivo for the first time. There was a definite variance in metabolism profile amongst the in vitro and in vivo effects.
EAM-2201 was incubated with human hepatocytes for 3 h in a CO2 incubator as well as metabolites of EAM-2201 have been created. The human liver specimen was homogenized as well as metabolites have been extracted. The urine specimen was hydrolyzed first with β-glucuronidase plus the metabolites were extracted.
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